Today, I tried to play for about an hour, using my PRS SE and my little Katana SS amp.
Before, I could set the amp on the Clean setting, add some distortion with a TS, and get a pretty good impression of my favorite Pink Floyd leads.
Today, it just wasn't there

I've lost most of the strength in my hands/fingers, and I can't dig in like is needed for that sound.
I ended up playing some of the old blues standards I learned when I got my first guitar, a Fender MusicMaster (which came with a free Champ), when I was 13 years old.
Then I tuned down, and had some fun with Sympathy for the Devil, which takes little to no hand strength

Now I feel a bit down, but I'm not going to give up. Maybe, if I keep at it, I'll get a decent sound back by this time next year.
Anybody else experience anything like this?