In my latest build (a D-clone in parts acquisition stage), I'll have 4, 8 and 16 ohm taps on the OT. I'm going to put together 2X12 cab to go with it. I'll most likely go with 8 ohm speakers, so the question is, should I wire the cab in series and use the 16 ohm tap or in parallel and use the 4 ohm tap?
So some people think you should use the maximum windings on your OT (which I believe would be the 16 ohm tap). Some think you should use the minimum windings to reduce distortion. I've read that series wiring will cut the damping factor in half (makes sense) but is that a good thing or a bad thing (an audible thing?) on a guitar amp?
Opinions sought!!

(Side question, or am I making a mistake with the 8 ohm speakers and should I instead get 16 ohm speakers and wire in parallel and use the 8 ohm tap?)